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(3-Oxo-1,3-dihydroisobenzofuran-1-yl)phosphonic acid dimethyl ester (CAS 61260-15-9)

(3-Oxo-1,3-dihydroisobenzofuran-1-yl)phosphonic acid dimethyl ester

Synonyms                   (1,3-dihydro-3-oxo-1-isobenzofuranyl)phosphonic acid dimethyl ester
                                      Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonate;

Packing  20'FCL Without /With pallets 40'FCL Without/With Pallets

1KG/Bag

25kg/Drums

N/A N/A
  • Specification
  • Feature&Application
  • Plant Details
  • FAQ
  • Properties
  • Standard

    Enterprise standard

    Appearance

    Almost white  powder

    Assay

    ≥99.0%

    Related substance 

    ≤1.0%

    Max single impurity

    ≤0.5%

  • Uses         (3-Oxo-1,3-dihydroisobenzofuran-1-yl)phosphonic acid dimethyl ester is intermediate of Olaparib

    Olaparib is used to treat cancers of the breast, ovary, fallopian tube, pancreas, prostate, or peritoneum (the membrane that lines the inside of your abdomen and covers some of your internal organs).

    Olaparib is sometimes used when the cancer has spread to other parts of the body, or when cancer has come back after treatment with other medications.

    Olaparib is sometimes used only if your cancer has a specific genetic marker (an abnormal "BRCA" or "HRR" gene). Your doctor will test you for this gene.

    Olaparib may also be used for purposes not listed in this medication guide


  • 1.  what is its main application?

    It is  intermediate of Olaparib

    2.  how many years we produced it, and what is its capactity

    It produced since 2018。 And capacity is 10mt annually.

     

    3. what is plant location and nearest port

    It located in a chemical zone Fujian province., and nearest port is Xiamen port

    4.  if doc. Support and audit available?

    Yes, VQ and allied tech. package is available for serious client.  Audit could be accepted for clients having business more than 1 year.

    5.  what other products are producing or plan to produce in this plant 

    Advanced pharmaceutical intermediates,e.g. intermediats of Pramipexole,Rivastigmine,Ramatroban,ivacaftor,Olaparib etc.

  • Property NameProperty ValueReference
    Molecular Weight 242.16 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18)
    XLogP3 0.4 Computed by XLogP3 3.0 (PubChem release 2019.06.18)
    Hydrogen Bond Donor Count 0 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
    Hydrogen Bond Acceptor Count 5 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
    Rotatable Bond Count 3 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
    Exact Mass 242.03441 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18)
    Monoisotopic Mass 242.03441 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18)
    Topological Polar Surface Area 61.8 Ų Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
    Heavy Atom Count 16 Computed by PubChem
    Formal Charge 0 Computed by PubChem
    Complexity 321 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
    Isotope Atom Count 0 Computed by PubChem
    Defined Atom Stereocenter Count 0 Computed by PubChem
    Undefined Atom Stereocenter Count 1 Computed by PubChem
    Defined Bond Stereocenter Count 0 Computed by PubChem
    Undefined Bond Stereocenter Count 0 Computed by PubChem
    Covalently-Bonded Unit Count 1 Computed by PubChem
    Compound Is Canonicalized Yes Computed by PubChem (release 2019.01.04)

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