3-Amino-1,2,3,4-tetrahydrocarbazol (CAS 61894-99-3)

3-amino-1,2,3,4-tetrahydrocarbazol

Synonyms 2,3,4,9-tetrahydro-1H-carbazol-3-amine

3-AMINO-1,2,3,4-TETRAHYDROCARBAZOLE

2,3,4,9-tetrahydro-1H-carbazol-3-amine

1H-Carbazol-3-amine, 2,3,4,9-tetrahydro-,

Documents: COA | MSDS

Packing

20'FCL Without /With pallets

40'FCL Without/With Pallets

1KG/Bag

25kg/Drums

N/A

Standard

Enterprise standard

Appearance

Almost white or light yellow crystal powder

Assay

≥98.0%

Water(K.F.)

≤1.0%
Molecular formula C₁₂H₁₄N₂
Molecular weight 186.256
Uses intermediate of Ramatroban

Ramatroban is used for the treatment of allergic rhinitis as an antagonist of the thromboxane receptor. It is also an antagonist of the DP2 receptor with IC50 values of 100-170 nM. It is more potent at the DP2 receptor than the TP receptor by 4-5 fold.
1. what is its main application?

It is intermediate of Ramatroban

2. how many years we produced it, and what is its capactity

It produced since 2010。 And capacity is 50 mt annually.

3. what is plant location and nearest port

It located in a chemical zone Fujian province., and nearest port is Xiamen port

4. if doc. Support and audit available?

Yes, VQ and allied tech. package is available for serious client. Audit could be accepted for clients having business more than 1 year.

5. what other products are producing or plan to produce in this plant

Advanced pharmaceutical intermediates，e.g. intermediats of Pramipexole，Rivastigmine，Ramatroban，ivacaftor，Olaparib etc.

Property Name	Property Value	Reference
Molecular Weight	186.25 g/mol	Computed by PubChem 2.1 (PubChem release 2019.06.18)
XLogP3-AA	1.9	Computed by XLogP3 3.0 (PubChem release 2019.06.18)
Hydrogen Bond Donor Count	2	Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
Hydrogen Bond Acceptor Count	1	Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
Rotatable Bond Count	0	Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
Exact Mass	186.115698 g/mol	Computed by PubChem 2.1 (PubChem release 2019.06.18)
Monoisotopic Mass	186.115698 g/mol	Computed by PubChem 2.1 (PubChem release 2019.06.18)
Topological Polar Surface Area	41.8 Å²	Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
Heavy Atom Count	14	Computed by PubChem
Formal Charge	0	Computed by PubChem
Complexity	216	Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
Isotope Atom Count	0	Computed by PubChem
Defined Atom Stereocenter Count	1	Computed by PubChem
Undefined Atom Stereocenter Count	0	Computed by PubChem
Defined Bond Stereocenter Count	0	Computed by PubChem
Undefined Bond Stereocenter Count	0	Computed by PubChem
Covalently-Bonded Unit Count	1	Computed by PubChem
Compound Is Canonicalized	Yes	Computed by PubChem (release 2019.01.04)

Standard	Enterprise standard
Appearance	Almost white or light yellow crystal powder
Assay	≥98.0%
Water(K.F.)	≤1.0%