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4-Acetamino cyclohexanone(CAS NO.: 27514-08-5)

4-N-acetyl-amino-cyclohexanone

Synonyms     N-(4-Oxocyclohexyl)acetamide

                       4-Acetamidocyclohexanone

                      4-(Acetylamino)cyclohexanone

                      4-acetamido-cyclohexanone

Documents: COA  | MSDS

Packing  20'FCL Without /With pallets 40'FCL Without/With Pallets

1KG/Bag

25kg/Drums

N/A N/A



  • Specification
  • Feature&Application
  • Plant Details
  • FAQ
  • Properties
  • Standard 

    Enterprise standard

    Appearance 

    white or light yellow crystal powder

    Assay

    ≥99%

    Water(K.F.) 

    ≤1.0%

  • Uses              4-Acetamino cyclohexanone is   intermediate of Pramipexole and  intermediate of Ramatroban

    Pramipexole is used alone or with other medications to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. It may also decrease the number of episodes of not being able to move ("on-off syndrome").

    This medication is also used to treat a certain medical condition (restless legs syndrome - RLS) that causes an unusual urge to move the legs. Symptoms usually occur at night along with uncomfortable/unpleasant feelings in the legs. This medication can decrease these symptoms and thereby improve sleep.

    Pramipexole is a dopamine agonist that works by helping to restore the balance of a certain natural substance (dopamine) in the brain.

    Ramatroban is used for the treatment of allergic rhinitis as an antagonist of the thromboxane receptor. It is also an antagonist of the DP2 receptor with IC50 values of 100-170 nM. It is more potent at the DP2 receptor than the TP receptor by 4-5 fold.

    Application:Parkinson's disease pramipexole intermediates and rhinitis drugs Ramatroban intermediates

    Attention:Sealed at room temperature

     


  • Advantage:Our factory is the biggest  manufacturer in China

  • 1.  what is its main application?

    It is  intermediate of Ramatroban & Pramipexole

    2.  how many years we produced it, and what is its capactity

    It produced since 2009。 And capacity is 200 mt annually.

     

    3. what is plant location and nearest port

    It located in a chemical zone Fujian province., and nearest port is Xiamen port

    4.  if doc. Support and audit available?

    Yes, VQ and allied tech. package is available for serious client.  Audit could be accepted for clients having business more than 1 year.

    5.  what other products are producing or plan to produce in this plant 

    Advanced pharmaceutical intermediates,e.g. intermediats of Pramipexole,Rivastigmine,Ramatroban,ivacaftor,Olaparib etc.

  • Chemical Safety

     

    Irritant

     

     

    Property NameProperty ValueReference
    Molecular Weight 155.19 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18)
    XLogP3-AA -0.2 Computed by XLogP3 3.0 (PubChem release 2019.06.18)
    Hydrogen Bond Donor Count 1 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
    Hydrogen Bond Acceptor Count 2 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
    Rotatable Bond Count 1 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
    Exact Mass 155.094629 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18)
    Monoisotopic Mass 155.094629 g/mol Computed by PubChem 2.1 (PubChem release 2019.06.18)
    Topological Polar Surface Area 46.2 Ų Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
    Heavy Atom Count 11 Computed by PubChem
    Formal Charge 0 Computed by PubChem
    Complexity 167 Computed by Cactvs 3.4.6.11 (PubChem release 2019.06.18)
    Isotope Atom Count 0 Computed by PubChem
    Defined Atom Stereocenter Count 0 Computed by PubChem
    Undefined Atom Stereocenter Count 0 Computed by PubChem
    Defined Bond Stereocenter Count 0 Computed by PubChem
    Undefined Bond Stereocenter Count 0 Computed by PubChem
    Covalently-Bonded Unit Count 1 Computed by PubChem
    Compound Is Canonicalized Yes Computed by PubChem (release 2019.01.04)

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